5 Lion's Mane Mushroom Benefits Explained + Studies

5 Lion's Mane mushroom benefits

Lion's Mane mushroom, a unique mushroom with cascading spines resembling a lion's mane, has been a staple in traditional medicine for centuries. But what is Lion’s Mane?

Native to the Northern Hemisphere and now gaining traction in the UK, this mushroom is not just a culinary delight but a promising potential remedy for various health concerns. Its historical significance spans various cultures, where it was revered not just for its taste but also for its theraputicl properties.

 Today, as the world leans towards natural remedies, Lion's Mane mushroom stands out as a beacon of hope for many seeking holistic health solutions.

5 Multifaceted Benefits of Lion's Mane

1. Cognitive Health and Neuroprotection

Lion's Mane mushroom, scientifically known as Hericium erinaceus, has garnered significant attention in the realm of neuroscientific research due to its potential cognitive-enhancing and neuroprotective properties.

a. Neurogenesis and Synaptic Plasticity:

Lion's Mane mushroom contains bioactive compounds, notably hericenones and erinacines, that are believed to stimulate the synthesis of nerve growth factor (NGF). NGF plays a pivotal role in the maintenance, survival, and regeneration of neurons.

b.  Nerve Recovery and Repair:

Injuries to the nervous system, whether peripheral or central, can have debilitating effects. The compounds in Lion's Mane mushroom have shown potential in accelerating the repair of damaged nerves. This could have implications for conditions like peripheral neuropathy or injuries where nerve damage is prevalent.

c. Mood Stabilization and Mental Health:

Beyond its neuroprotective capabilities, Lion's Mane may also offer benefits for mental health such as ADHD. Some studies suggest that it can alleviate symptoms of anxiety and depression. The mechanism behind this is believed to be linked to its ability to boost NGF, which not only supports neuron health but also plays a role in mood regulation.

5 benefits of lions mane

d. Brain Health Promotion:

A notable study titled "Lion’s Mane Mushroom- From Culinary to Medicine" delves deep into the mushroom's multifaceted benefits. This research underscores Lion's Mane's positive impact on brain health, emphasising its potential in nerve recovery and mood stabilisation. Such studies provide a scientific foundation for the traditional claims of Lion's Mane's cognitive benefits.

e. Potential for Alzheimer's and Dementia:

Given its role in promoting neurogenesis and synaptic plasticity, there's growing interest in the potential application of Lion's Mane in the treatment or prevention of neurodegenerative diseases like Alzheimer's and dementia.

2. Antidepressant Effects

A recent study titled "Potential antidepressant effects of a dietary supplement derived from the chlorella and lion's mane mushroom complex" indicates that Lion's Mane may have properties that help in reducing depressive symptoms.

3. Oxidative Stress Reduction and Anti-inflammatory Properties

Research has shown that Lion's Mane mushroom can potentially counteract oxidative stress and inflammation within the neuron-glia system by enhancing the body's antioxidant defenses and reducing inflammatory responses.

4. Gastric Health, Heart Health, and Immunity Enhancement

Beyond cognitive benefits, Lion's Mane has shown promise in areas like gastric health, heart health, blood sugar regulation, and immunity enhancement. These multifaceted benefits make Lion's Mane a sought-after supplement for holistic health.

5. Our Defence Mechanism

Lion’s Mane mushroom contains beta-glucans, which are known to have immune-supporting properties. These compounds may help to activate immune cells, such as macrophages and natural killer cells, which may aid in fighting off infections.

Naturecan's Lion's Mane Offerings

Naturecan recognises the potential of Lion's Mane and has harnessed its power in two standout products: mixed mushroom complex and Mushroom gummies.

 These products are not just about the mushroom but the quality of the Lion’s Mane extract they contain, ensuring maximum benefits for the consumers.

Naturecan's commitment to quality and purity ensures that consumers get the best of Lion's Mane's benefits without any additives or fillers.

Naturecan's Lions mane offering

Dosage, Frequency, and Extracts

While the potential benefits of Lion's Mane are evident, how much should one consume? The answer lies in the potency of the Lion’s Mane extract and the desired health outcomes. It's essential to follow recommended Lion's Mane dosages, especially when starting.

Over time, one can adjust based on individual experiences and needs. The extraction process is crucial as it determines the concentration of bioactive compounds. Naturecan ensures a high-quality extraction process, making their mushroom complex and mushroom gummies potent and effective.

Do Lion's Mane have any side effects?

Here are some Lion’s Mane side effects that you should consider before adding mushrooms to your everyday routine:

1.  Digestive Upset: Some individuals might experience digestive issues after consuming Lion's Mane.

2. Skin Rashes: Allergic reactions, manifesting as skin rashes, have been reported by a few users.

3. Hormonal Considerations: There are ongoing studies looking into Lion's Mane's potential effects on oestrogen levels.

4. Mental Health Implications: Some anecdotal reports suggest that Lion's Mane might cause anxiety in certain individuals, though this is not conclusively proven.

5. Potential Drug Interactions: Before starting Lion's Mane, it's essential to consult with a healthcare professional, especially if one is on medication or has underlying health conditions.

Interactions, Precautions, and Drug Considerations

Before diving into the world of Lion's Mane, it's essential to consider any existing medical conditions or medications. While Lion's Mane is generally safe, interactions with certain drugs or conditions might require caution.

It's always recommended to consult with a healthcare professional before starting any new supplement, especially if one is on medication or has underlying health conditions.

Lion’s Mane vs Ashwagandha: Comparing Lion's Mane with Other Supplements

a. Lion's Mane: The Brain Booster Lion's Mane is primarily known for its neuroprotective properties. Its bioactive compounds have been shown to stimulate the production of nerve growth factor (NGF), which plays a crucial role in maintaining and organising neurons. This makes Lion's Mane particularly beneficial for cognitive health, memory enhancement, and nerve repair.

b. Ashwagandha: The Stress Reliever Ashwagandha, also known as Indian ginseng, is a revered herb in Ayurvedic medicine. It's best known for its adaptogenic properties, meaning it helps the body adapt to stress. Ashwagandha has been shown to reduce cortisol levels, combat anxiety, and improve sleep patterns. While it also offers cognitive benefits, its primary strength lies in balancing hormones and reducing stress.

Interactions with Other Supplements and Medications

Is Lion's Mane safe? While Lion's Mane is generally considered safe, it's essential to be cautious when combining it with other supplements or medications. For instance:

1. Antidiabetic Medications: Lion's Mane may lower blood sugar levels, so combining it with antidiabetic medications might cause hypoglycemia.

2.  Anticoagulant and Antiplatelet Drugs: There's potential for Lion's Mane to increase the risk of bleeding when taken with these medications.

3. Other Nootropic Supplements: Combining Lion's Mane with other cognitive enhancers, like Ginkgo Biloba or Rhodiola, might amplify the effects. While this can be beneficial, it's essential to monitor for any adverse reactions.

Naturecan Lions Mane Gummies

Historical and Cultural Significance of Lion's Mane

Lion's Mane has a rich history that dates back centuries. In traditional Chinese medicine, it was revered for its ability to nourish the gut and the brain. Ancient practitioners believed in its power to boost cognitive functions and improve digestive health. In Japan, it was often consumed in teas and soups, not just for its unique flavour but also for its medicinal properties.

The Science Behind Lion's Mane

The benefits of Lion's Mane are not just based on anecdotal evidence; modern science has begun to validate its numerous health benefits.

The mushroom contains two unique compounds, hericenones and erinacines, which are believed to stimulate the production of nerve growth factor (NGF).

NGF is crucial for the health and maintenance of neurons in the brain. This scientific backing has led to a surge in the popularity of Lion's Mane, especially among those seeking cognitive enhancement and neuroprotection.

How to Choose the Right Lion's Mane Supplement

With the growing popularity of Lion's Mane, the market is flooded with various supplements claiming to offer the best Lion’s Mane extract. So, how do you choose the best Lion’s Mane supplement? Here are some pointers:

1. Source: Ensure that the supplement is sourced from reputable farms that practise organic cultivation. It is also essential that the extract is taken from the fruiting body of the mushroom.

2. Extraction Process: The method of extraction determines the potency of the supplement. Look for products that use a dual extraction process.

3. Potency: Check the percentage of active compounds like hericenones and erinacines.

4. Reviews: Always check reviews and testimonials to gauge the efficacy of the product.

Learn more about how long lion’s mane takes to work here.

How to choose the right lions mane gummies

Incorporating Lion's Mane into Your Diet

Apart from supplements, Lion's Mane can be incorporated into your diet in various ways. Fresh Lion's Mane mushrooms can be sautéed, grilled, or used in soups.

They have a seafood-like taste, often compared to crab or lobster. For those who prefer a sweeter intake, Naturecan's Lion's Mane gummies are a perfect choice.

Embracing the Power of Nature with Lion's Mane

In an era where synthetic drugs and fast-paced lifestyles dominate, turning to nature for healing and wellness can be transformative.

Lion's Mane in the form of our mushroom gummies and mushroom complex, offers a blend of potential cognitive, neurological, and overall health benefits, making it a must-have in everyone's wellness arsenal.

With Naturecan's commitment to quality and purity, one can be assured of harnessing the full potential of this magical mushroom.


1. Lai, P. L., Naidu, M., Sabaratnam, V., Wong, K. H., David, R. P., Kuppusamy, U. R., Abdullah, N., & Malek, S. N. A. (2013, January 1). Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International Journal of Medicinal Mushrooms; Begell House. https://doi.org/10.1615/intjmedmushr.v1

2. Wong, K. H., Naidu, M., David, R. P., Bakar, R., & Sabaratnam, V. (2012, January 1). Neuroregenerative Potential of Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Higher Basidiomycetes), in the Treatment of Peripheral Nerve Injury (Review). International Journal of Medicinal Mushrooms; Begell House. https://doi.org/10.1615/intjmedmushr.v14.i5.10

3. Rootman, J. M., Kryskow, P., Harvey, K., Stamets, P., Santos-Brault, E., Kuypers, K. P. C., Polito, V., Bourzat, F., & Walsh, Z. (2021, November 18). Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers. Scientific Reports; Nature Portfolio. https://doi.org/10.1038/s41598-021-01811-4

4. Gilbert, D., & Williams, J. O. (2023, September 30). Lion’s Mane Mushroom- From Culinary to Medicine. Annals of Innovation in Medicine. https://doi.org/10.59652/aim.v1i2.55

5. Lowe, S., Usowicz, M. M., & Hodge, J. (2018, July 17). Neuronal overexpression of DYRK1A/minibrain alters motor decline, neurodegeneration and synaptic plasticity in Drosophila. https://doi.org/10.1101/370924

6. Chou, M. Y., Ho, J. H., Huang, M., Chen, Y., Yang, M., Lin, L., Chi, C. H., Yeh, C. H., Tsao, T. Y., Tzeng, J. K., Hsu, R. J. C., Huang, P., Lu, W., Li, P., & Wang, M. (2022, September 2). Potential antidepressant effects of a dietary supplement from the chlorella and lion’s mane mushroom complex in aged SAMP8 mice. Frontiers in Nutrition; Frontiers Media. https://doi.org/10.3389/fnut.2022.977287

7. Kushairi, N., Phan, C. W., Sabaratnam, V., David, P., & Naidu, M. (2019, August 1). Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia. Antioxidants; Multidisciplinary Digital Publishing Institute. https://doi.org/10.3390/antiox8080261

8. Gilbert, D., & Williams, J. O. (2023, September 30). Lion’s Mane Mushroom- From Culinary to Medicine. Annals of Innovation in Medicine. https://doi.org/10.59652/aim.v1i2.55

9. Rossi, P., Cesaroni, V., Brandalise, F., Occhinegro, A., Ratto, D., Perrucci, F., Lanaia, V., Girometta, C. E., Orrù, G., & Savino, E. (2018, January 1). Dietary Supplementation of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), and Spatial Memory in Wild-Type Mice. International Journal of Medicinal Mushrooms; Begell House. https://doi.org/10.1615/intjmedmushrooms.2018026241

10. Lai, P. L., Naidu, M., Sabaratnam, V., Wong, K. H., David, R. P., Kuppusamy, U. R., Abdullah, N., & Malek, S. N. A. (2013, January 1). Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International Journal of Medicinal Mushrooms; Begell House. https://doi.org/10.1615/intjmedmushr.v15.i6.30

11. Salve, J., Pate, S., Debnath, K., & Langade, D. (2019, December 25). Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus; Cureus, Inc. https://doi.org/10.7759/cureus.6466

12. Di Rocco, M., Soligo, M., Manni, L., & Aloe, L. (2018, November 2). Nerve Growth Factor: Early Studies and Recent Clinical Trials. Current Neuropharmacology; Bentham Science Publishers. https://doi.org/10.2174/1570159x16666180412092859