Does CBD Interact With Medications?

Does CBD interact with medications

CBD oil has gained a lot of attention in recent years for its potential health benefits. This oil is extracted from the cannabis plant and has been found to have a wide range of therapeutic properties.

While CBD oil is not a cure-all, it has shown promise in treating a variety of conditions, including anxiety, depression, chronic pain, and inflammation.

Despite being derived from the cannabis plant, CBD oil does not produce the psychoactive effects of cannabis use. This is because CBD oil contains very low levels of THC, the chemical that causes a “high” when smoked or ingested.

As more people become interested in the potential benefits of CBD oil, its use has become increasingly popular. CBD oil can be found in various forms, including CBD capsules, CBD Oil tinctures, and CBD balms.

Understanding CBD Oil

The components of CBD oil are known as:

  • CBD
  • Other cannabinoids
  • Terpenes/flavonoids
  • Carrier oil

CBD oil is made by extracting CBD, one of the main cannabinoids found in the cannabis plant.

This CBD extraction process typically involves using a solvent, such as CO2 or ethanol, to separate the CBD from the rest of the plant material.

The resulting product is then diluted with a carrier oil, such as hemp seed oil or coconut oil.

It’s important to note that not all CBD oils are created equal. The quality and potency of CBD oil can vary widely depending on the manufacturer and the extraction method used.

When choosing a CBD oil, looking for one tested by a third-party laboratory for purity and potency is essential.

Potential Benefits

CBD Oil and Pain

One of CBD oil's most commonly cited potential benefits is its ability to alleviate pain. Research has shown that CBD oil may effectively reduce pain associated with conditions such as arthritis, multiple sclerosis, and neuropathic pain.

CBD works by interacting with the body's endocannabinoid system (ECS), which regulates a wide range of bodily functions, including pain perception.

When CBD is ingested, it binds to the CB1 and CB2 receptors in the ECS, which can help to reduce inflammation and alleviate pain.

CBD Oil and Anxiety

Another potential benefit of CBD oil is its ability to reduce anxiety. Studies have shown that CBD may effectively reduce symptoms of anxiety disorders such as generalised anxiety disorder, social anxiety disorder, and post-traumatic stress disorder (PTSD).

However, it is essential to note that CBD is not a cure for anxiety and should not replace professional treatment.

One concern many people have when considering CBD oil is whether it will interact with their medications.

CBD can indeed interact with certain medications, so it is crucial to speak with a healthcare professional before using CBD oil if you are taking any medication.

What are the Different Types of CBD Oil?

There are three main types of CBD oil, full-spectrum, broad-spectrum, and isolate.

 – Full-spectrum CBD oil contains all the compounds in the cannabis plant, including THC, the psychoactive component that produces the “high” associated with marijuana use.

 – Broad-spectrum CBD oil is similar to full-spectrum, but it has been processed to remove almost all traces of THC.

  – Isolate CBD oil is the purest form of CBD, containing only the
CBD compound.

It’s important to note that while full-spectrum CBD oil contains THC, it is typically very low and unlikely to produce any psychoactive effects.

What are the different types of CBD oil

However, if you are subject to drug testing, even trace amounts of THC can appear on a drug test, so you may want to consider using broad-spectrum or isolate CBD oil.

CBD Oil and Medications

If you’re considering using 5% CBD oil in combination with medications, it’s essential to understand how these substances may interact. CBD can affect how your body metabolises certain medications, which can cause them to be less effective or more potent than intended.

One of the enzymes responsible for breaking down medications in the liver, CYP450, is also involved in metabolising CBD.

This means that taking CBD oil alongside medications metabolised by CYP450 may cause the medication to be broken down more slowly.

This can lead to higher medication levels in the bloodstream, increasing the risk of side effects.

CBD Oil and medications

What do CYP450 enzymes do?

These enzymes play a pivotal role in metabolising many drugs/medicines, including antidepressants, blood thinners, and anti-seizure medications.

 The interaction between CBD and medications metabolised by CYP450 can lead to a slower medication breakdown.

This means that the medication may stay in the bloodstream for longer, potentially leading to higher levels of the drug in the body. This can increase the risk of side effects, such as drowsiness, dizziness, and nausea.

It is important to note that not all medications are metabolised by CYP450 enzymes. Therefore, not all medications will interact with CBD.

However, if you are currently taking medication and are considering starting use of a low dose of 5% CBD oil, it is essential to talk to your doctor first. Your doctor can advise whether CBD and current medications are safe.

Which Medications Can CBD Interact With?

If you are taking any medication, speaking with your doctor before using CBD oil is essential. This is because CBD can interact with certain medications, potentially causing side effects or reducing the effectiveness of the medication. Some medications that may interact with CBD include:

 – Blood Thinners: CBD can increase the risk of bleeding when taken with blood-thinning medications such as warfarin. This can lead to serious health problems.

  – Antidepressants: CBD can increase the levels of certain antidepressants, such as SSRIs (selective serotonin reuptake inhibitors), in the blood. This can lead to a higher risk of side effects, such as drowsiness, dizziness, and confusion.

 – Anti-anxiety Medications: CBD can interact with anti-anxiety medications such as benzodiazepines, leading to increased sedation and drowsiness.

 – Anti-seizure Medications: CBD may interact with anti-seizure medications, reducing their effectiveness and potentially leading to seizures.

 It is important to note that the potential interactions between CBD and medications are still being studied, and more research is needed to understand the effects entirely.

However, it is always best to err on the side of caution and speak with your doctor before using CBD oil if you are taking any medication.

Possible side effects of combining CBD Oil and Medications

The answer is not straightforward, and it depends on several factors. Firstly, it is essential to understand how CBD oil works in the body.

CBD interacts with the endocannabinoid system (ECS), regulating various functions such as mood, appetite, sleep, and pain. CBD is known to enhance the functioning of the ECS, which is why it is effective in treating various medical conditions.

When CBD is taken with other medications, it can interact with the enzymes responsible for metabolising these drugs. This interaction can either increase or decrease the effectiveness of the medication.

Some medications can also interact with CBD oil, leading to adverse side effects. Therefore, consulting a healthcare professional before taking CBD oil and other medications is crucial.

Some of the possible side effects of combining CBD oil and medications include:

-  Increased risk of bleeding: CBD oil can inhibit the activity of platelets, which are responsible for blood clotting. If taken along with medications such as blood thinners, this can increase the risk of bleeding.

- Altered drug metabolism: CBD oil can interact with enzymes in the liver responsible for metabolising medications such as benzodiazepines, antipsychotics, and opioids. This can lead to altered drug metabolism and increased or decreased medication levels in the body.

- Increased liver toxicity: Some medications are known to cause liver toxicity, and when taken along with CBD oil, this risk can be increased. This is especially true for medications such as acetaminophen, commonly used for pain relief.

- Reduced effectiveness of medications: CBD oil has been shown to reduce the effectiveness of some medications, such as the anti-seizure medication clobazam. This can lead to increased seizure activity and the need for higher doses of the medication.

It is essential for individuals considering taking CBD oil and medications to consult with their healthcare provider beforehand.

This is especially true for individuals taking medications for chronic conditions such as epilepsy, anxiety, or depression.

Always consult with your healthcare provider: Your healthcare provider can help you determine if taking CBD oil along with your medication is safe and effective for

How to Use CBD Oil Safely with Medications

If you have spoken with your doctor and have decided to use CBD oil alongside your medication, it is essential to use it safely. Here are some tips to keep in mind:

1. Start with a low dose: It is always best to start with a low dose of CBD and gradually increase if needed. This can help you avoid any potential side effects or interactions.

2. Be consistent: If you are taking CBD oil alongside medication, it is essential to be consistent with your dosing schedule. This can help you avoid sudden changes in medication levels in the bloodstream.

3. Monitor for side effects: Monitor for any potential side effects when taking CBD oil with medication. This can include drowsiness, dizziness, nausea, or changes in appetite.

4. Inform your doctor: It is essential to inform your doctor of any changes in your medication regimen, including adding CBD oil.

Your doctor can monitor your progress and adjust your medication as needed.

How to use CBD Oil safely with medications

Factors that affect interactions between CBD Oil and Medications

CBD oil can interact with other drugs as with any medication or supplement. These interactions can sometimes be dangerous, so it is essential to understand the factors that can affect how CBD oil interacts with medications.

Dosage and Frequency of Use

The dosage and frequency of use of CBD oil can affect how it interacts with other medications. Higher doses of CBD oil are more likely to interact with medications, primarily if the liver metabolises the medication. This is because CBD oil can inhibit the activity of certain liver enzymes, which can slow down the metabolism of other drugs.

It is also essential to consider how often CBD oil is used. If CBD oil is used daily, it is more likely to interact with other medications than if it is only used occasionally.

Naturecan CBD Dosage Calculator

Type of Medication

The type of medication being taken can also affect how CBD oil interacts with the body. The liver metabolises some medications, while others are metabolised by other organs or eliminated through the kidneys.

Medications metabolised by the liver are more likely to interact with CBD oil, as they can inhibit the liver enzymes that metabolise them. This can lead to an accumulation of the medication in the body, increasing the risk of side effects.

It is important to note that CBD oil can interact with medications differently depending on the medication and the individual’s body. Therefore, it is recommended that individuals speak with their doctor before taking CBD oil in combination with any medications.

Metabolism and health condition of the individual

This plays a vital role in the way medications interact with CBD oil. Many people who use CBD oil are often on medication for various health conditions. This raises the concern of whether or not taking CBD oil with medications is safe.

Many people use medications for different health conditions, such as pain, anxiety, depression, seizures, and insomnia. The interaction between medications and CBD oil can affect how the body metabolises the medication, leading to unwanted side effects or reduced effectiveness.

The liver plays a crucial role in metabolising CBD oil and medications. The liver contains enzymes that break down bodily substances, including medications and CBD oil. When CBD oil and medications are taken together, the liver may not be able to metabolise them correctly, accumulating the substance in the body.


CBD oil has shown great promise as a natural remedy for various ailments. Still, it is essential to understand the interactions between CBD oil and medications.

As we have seen, CBD can interact with some medications by increasing or decreasing their effects or amplifying their side effects. Therefore, it is crucial to consult with a healthcare provider before using CBD oil, especially if you are taking any medication. That being said, CBD oil has a lot of potential benefits for many people, and as such, it is worth exploring. However, it is essential to remember that each person’s body chemistry is different; therefore, CBD oil’s effects can vary from person to person.

In conclusion, CBD oil is a powerful natural remedy gaining popularity for its many potential benefits. However, it is essential to understand the interactions between CBD oil and medications to avoid any potential complications. If you are considering using CBD oil, it is crucial to consult with your healthcare provider to determine the best course of action for your specific needs. With the right guidance and information, CBD oil can be a valuable addition to your health and wellness routine.